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EVA-System — Embryo Vitality Assistance

EVA-System is the effective method of embryo culturing, excusively applied at MAMA Clinic. The significant advantage of EVA-System against its’ analogues is the unique composition of culture medium containing specific molecules referred to as OLI

EVA-System is the effective method of embryo culturing, excusively applied at MAMA Clinic. The significant advantage of EVA-System against its’ analogues is the unique composition of culture medium containing specific molecules referred to as OLIGONUCLEOTIDES.

The inclusion of OLIGONUCLEOTIDES in the embryo-culturing environment is the advanced high-tech solution for applied Biomedicine and the output of a long-term joint scientific research project carried out by Moscow State University Embryology Department and MAMA Clinic specialists.

OLIGONUCLEOTIDES are short molecules with wide range of applications in genetics. They are naturally featured with the motion that stimulates the launch of the protective functions of the embryo cells. In other words, whenever the embryo is impaired for some reason, the presence of the OLIGONUCLEOTIDES in culture environment will give it the support on molecular level, stimulation the launch of biosynthesis, which is essential for growing and developing to further stages. The impact of OLIGONUCLEOTIDES on the embryo tissue reduces the cells fraction and therefore increases its’ survival potential.

It’s been clinically proven that the application of EVA-System leads to a significant raise of pregnancy rates in IVF protocols.

The leading research labs in Moscow and Saint Petersburg have held series of testing via microbiologic research (QRT-PCR, laser confocal microscopy) to confirm the efficiency and safety of EVA-System application in infertility treatment.

The composition of OLIGONUCLEOTIDES medium in embryo-culturing environment, and the methods of its application in IVF have been patented by MAMA Clinic (see patent).

Embryo Vitality Assistance System is included in IVF programs for infertility treatments at MAMA Clinic exclusively.

The results of this research and its practical application have been officially presented and recognized at several professional events for reproductive medicine, such as:   

  • «BioScience 2005 – from genes to systems» International Conference, Glasgow, UK, 2005. (see the news and publications on the topic);      
  • 3d International Congress of ART «Recent aspects of Assisting Reproductive Technologies», Moscow, Russia, 2006. (see the news and publications on the topic);      
  • The 22nd Annual Meeting of the ESHRE, Prague (Czech republic) 2006 (see the news and publications on the topic);  
  • 4th International Congress of ART «Recent aspects of Assisted Reproductive Technologies», Moscow, Russia, 2007 г. (see the news and publications on the topic)      
  • International Congress «15th World Congress of Gynecological Endocrinology», Florence, Italy, 2012 (see the news and publications on the topic). 

The summary of the research results on EVA-System have been published in:  

  • “Reproduction Problems” Magazine, 2006, Volume 12, #1, pages 46-52 (see publication),      
  • Magazine, 2008, Volume 44, pages 1290-1293 (see publication).


Julia Zaikova

Anesthesiologist