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ICSI-MAQS — Microscopic Sperm Quality System

ICSI-MAQS is the method for selecting the spermatozoids most suitable for further implantation into the uterus. It is based on the ultra-fine structure specifications and main morphological attributes. The embryologists at MAMA Clinic have been applying MAQS technique for ICSI (Intra Cytoplasmic Sperm Injection) and ICSI-MAQS fertilization.

Morphological selection is currently the most widely used method of perspective sperm detection for ICSI. It is based on the simple concept that the sperm with less visible alterations is more likely to have the adequate set of chromosomes and is therefore more suitable for implantation with better chances for successful conception and less likehood of further miscarriage. The more elaborate method of cytological semen evaluation requires the ultimate accuracy to provide for better chances for success. This primarily implies the usage of high-tech microscope with greater magnification and resolving power, additionally equipped with the optical device for exhaustive cell examination.

At MAMA Clinic, we apply the three-stages MAQS method:

  1.  It starts with the selection and discard of the sperm with visible abnormalities based on light microscopic examination, followed by
  2. The application of phase contrast, which allows performing the analysis necessary to define the essential particles of sperm head structure: the nucleus and the acrosome. This will help to identify possible pathology and dysfunction of the chromosome set. We then move on to
  3. The analysis of ultra-fine structures of the sperm head, performed with the modulation contrast, which allows identifying such anomalies as vacuolization, or irregular liquid inclusions, etc.

Summing up the above information on ICSI-MAQS, it can be stated with certainty that at MAMA Clinic, we use the most diversified and exhaustive analysis for sperm selection, based on the various indications of its potential for conception and successful development of the fetus. This technique is applied via the newer high-tech equipment, which, in combination with highly qualified lab staff, guarantees the quality analysis of the finest structural features of the sperm.


Julia Zaikova

Anesthesiologist