CA&CA — Cytogenic Analysis and detection of Chromosomal Aberration

CA&CA is the method of Karyotype aberrations identification. Karyotype is the characterization of the chromosomal complement in human being. Karyotyping is a test to examine chromosomes in a sample of cells, which helps picture the presence, appearance, location and distribution of eu- and heterochromatin in chromosomes and identify genetic problems as possible cause of a disease or disorder. Normally, human cells (as well as embryo cells) contain 46 chromosomes in 23 pairs. That is 22 autosomes, which are the same for men and women, and one pair that determines our sex: a female has X chromosome (XX), whereas a male has an X and a Y in 23d pair (XY).

At MAMA Clinic, carry out karyotype aberrations analysis (intra- and inter-chromosomal abnormalities). The analysis involves applying cytogenetic technique on the blood lymphocytes culture and both methods of differentiated and monochrome staining. It enables carrying out exhaustive cytogenetic examination of chromosomal number and structure to detect translocations, inversions, deletions, duplications and insertions.

It is possible that even being present in an adult individual’s organism, chromosomal numeric and morphologic alterations have no impact on his/her health and show no signs of presence whatsoever, but they will inevitably affect the fertility perspective or/and the ability to gestate and give birth to healthy children. Karyotyping with aberrations is meant to assist in detecting the infertility cause accurately and compiling a sufficient IVF fertility treatment program.

Julia Zaikova